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The antihypertension drug doxazosin suppresses JAK/STATs phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis

Doxazosin, a commonly prescribed treatment for patients with benign prostatic hyperplasia, serves as an α1-blocker of the adrenergic receptors. In this study, we calculated its effect on the ovarian carcinoma cells. Doxazosin induces dose-dependent growth suppression and is additively activated thro...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Park, Mi Sun, Kim, Boh-Ram, Kang, Sokbom, Kim, Dae-Yong, Rho, Seung Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279443/
https://ncbi.nlm.nih.gov/pubmed/25568671
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