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Role of endogenous 4-1BB in the development of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is characterized by the production of autoantibodies directed against nuclear antigens including nucleosomes and DNA. To determine the role of T-cell costimulatory molecule 4-1BB in the regulation of SLE, MRL-Fas(lpr) (lpr) mice deficient in 4-1BB (lpr/4-1BB(–/–))...

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Bibliografske podrobnosti
Main Authors: Vinay, Dass S, Choi, Jae H, Kim, Jung D, Choi, Beom K, Kwon, Byoung S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266025/
https://ncbi.nlm.nih.gov/pubmed/17608689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02653.x
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