Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice

To explore the roles of 4-1BB (CD137) and CD28 in corneal transplantation, we examined the effect of 4-1BB/4-1BB ligand (4-1BBL) and/or CD28/CD80/CD86 blockade on corneal allograft survival in mice. Allogeneic corneal transplantation was performed between two strains of wild-type (WT) mice, BALB/c a...

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Detalhes bibliográficos
Main Authors: Asai, Tatsuhiko, Choi, Beom K, Kwon, Patrick M, Kim, Won Y, Kim, Jung D, Vinay, Dass S, Gebhardt, Bryan M, Kwon, Byoung S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265952/
https://ncbi.nlm.nih.gov/pubmed/17376197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02581.x
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