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New emerging targets in cancer immunotherapy: CD137/4-1BB costimulatory axis
CD137 (4-1BB) is a surface glycoprotein that belongs to the tumour necrosis factor receptor family (TNFRSF9). Its expression is induced on activation on a number of leucocyte types. Interestingly, for cancer immunotherapy, CD137 becomes expressed on primed T and natural killer (NK) cells, which on l...
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| Publicado no: | ESMO Open |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7333812/ https://ncbi.nlm.nih.gov/pubmed/32611557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2020-000733 |
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