CD45-associated protein promotes the response of primary CD4 T cells to low-potency T-cell receptor (TCR) stimulation and facilitates CD45 association with CD3/TCR and Lck

Although it is clear that the CD45 tyrosine phosphatase is required for efficient T-cell activation and T-cell development, the factors that regulate CD45 function remain uncertain. Previous data have indicated that there is an association of CD45 with CD4 and the T-cell receptor (TCR) complex contr...

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Hlavní autoři: Leitenberg, David, Falahati, Rustom, Lu, Dan Dan, Takeda, Akiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2007
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265975/
https://ncbi.nlm.nih.gov/pubmed/17428310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02602.x
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