Lck Mediates Signal Transmission from CD59 to the TCR/CD3 Pathway in Jurkat T Cells

The glycosylphosphatidylinositol (GPI)-anchored molecule CD59 has been implicated in the modulation of T cell responses, but the underlying molecular mechanism of CD59 influencing T cell signaling remained unclear. Here we analyzed Jurkat T cells stimulated via anti-CD3ε- or anti-CD59-coated surface...

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Bibliografische gegevens
Hoofdauteurs: Lipp, Anna M., Juhasz, Kata, Paar, Christian, Ogris, Christoph, Eckerstorfer, Paul, Thuenauer, Roland, Hesse, Jan, Nimmervoll, Benedikt, Stockinger, Hannes, Schütz, Gerhard J., Bodenhofer, Ulrich, Balogi, Zsolt, Sonnleitner, Alois
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893272/
https://ncbi.nlm.nih.gov/pubmed/24454946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085934
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