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The Complex Function of Hsp70 in Metastatic Cancer

Elevated expression of the inducible heat shock protein 70 (Hsp70) is known to correlate with poor prognosis in many cancers. Hsp70 confers survival advantage as well as resistance to chemotherapeutic agents, and promotes tumor cell invasion. At the same time, tumor-derived extracellular Hsp70 has b...

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Detalhes bibliográficos
Main Authors: Juhasz, Kata, Lipp, Anna-Maria, Nimmervoll, Benedikt, Sonnleitner, Alois, Hesse, Jan, Haselgruebler, Thomas, Balogi, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980608/
https://ncbi.nlm.nih.gov/pubmed/24362507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6010042
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