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Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase During Thymocyte Development
In CD45 deficient animals there is a severe defect in thymocyte positive selection, resulting in an absence of mature T cells and the accumulation of thymocytes at the double positive stage of development. However, the signaling defect(s) responsible for the block in development of mature single pos...
Gorde:
| Egile Nagusiak: | , |
|---|---|
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671959/ https://ncbi.nlm.nih.gov/pubmed/18941197 |
| Etiketak: |
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