Genetic and immunochemical evidence for CD4-dependent association of p56lck with the alpha beta T-cell receptor (TCR): regulation of TCR-induced activation.

Recent observations suggest that the tyrosine kinase p56lck is involved in the transduction of transmembrane signals through the antigen specific T cell receptor (TCR) in CD4+ T cells. By means of in vitro kinase assays, we have found that p56lck coprecipitated with the TCR from lysates of a murine...

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Bibliographic Details
Main Authors: Díez-Orejas, R, Ballester, S, Feito, M J, Ojeda, G, Criado, G, Ronda, M, Portolés, P, Rojo, J M
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC394782/
https://ncbi.nlm.nih.gov/pubmed/7905824
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