Genetic and immunochemical evidence for CD4-dependent association of p56lck with the alpha beta T-cell receptor (TCR): regulation of TCR-induced activation.

Recent observations suggest that the tyrosine kinase p56lck is involved in the transduction of transmembrane signals through the antigen specific T cell receptor (TCR) in CD4+ T cells. By means of in vitro kinase assays, we have found that p56lck coprecipitated with the TCR from lysates of a murine...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Díez-Orejas, R, Ballester, S, Feito, M J, Ojeda, G, Criado, G, Ronda, M, Portolés, P, Rojo, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7905824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06238.x
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