Increased levels of interferon-γ primed by culture filtrate proteins antigen and CpG-ODN immunization do not confer significant protection against Mycobacterium tuberculosis infection

The results of various animal model studies of tuberculosis (TB) suggest that culture filtrate proteins (CFPs), which are antigens secreted by Mycobacterium tuberculosis, are largely responsible for improvements in TB vaccines. The great obstacle to developing protein subunit vaccines is that adjuva...

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Bibliografiske detaljer
Main Authors: Morais da Fonseca, Denise, Lopes Silva, Célio, Oliveira e Paula, Marina, Garcia Soares, Edson, Marchal, Gilles, Horn, Cynthia, Deperon Bonato, Vânia Luiza
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265969/
https://ncbi.nlm.nih.gov/pubmed/17433075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02597.x
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