Mycobacterium tuberculosis Culture Filtrate Proteins plus CpG Oligodeoxynucleotides Confer Protection to Mycobacterium bovis BCG-Primed Mice by Inhibiting Interleukin-4 Secretion

Culture filtrate proteins (CFP) are potential targets for tuberculosis vaccine development. We previously showed that despite the high level of gamma interferon (IFN-γ) production elicited by homologous immunization with CFP plus CpG oligodeoxynucleotides (CFP/CpG), we did not observe protection whe...

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Detalhes bibliográficos
Main Authors: Fonseca, Denise Morais da, Silva, Celio Lopes, Wowk, Pryscilla Fanini, Paula, Marina Oliveira e, Ramos, Simone Gusmão, Horn, Cynthia, Marchal, Gilles, Bonato, Vânia Luiza Deperon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786481/
https://ncbi.nlm.nih.gov/pubmed/19752029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00580-09
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