Increased levels of interferon-γ primed by culture filtrate proteins antigen and CpG-ODN immunization do not confer significant protection against Mycobacterium tuberculosis infection

The results of various animal model studies of tuberculosis (TB) suggest that culture filtrate proteins (CFPs), which are antigens secreted by Mycobacterium tuberculosis, are largely responsible for improvements in TB vaccines. The great obstacle to developing protein subunit vaccines is that adjuva...

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Detalhes bibliográficos
Main Authors: Morais da Fonseca, Denise, Lopes Silva, Célio, Oliveira e Paula, Marina, Garcia Soares, Edson, Marchal, Gilles, Horn, Cynthia, Deperon Bonato, Vânia Luiza
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265969/
https://ncbi.nlm.nih.gov/pubmed/17433075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02597.x
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