Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals

Oligodeoxynucleotides (ODN) with unmethylated deoxycytidyl-deoxyguanosine dinucleotides (CpG-ODNs) stimulate Toll-like receptor 9 (TLR9) in plasmacytoid dendritic cells (pDC) and B cells and activate innate and adaptive immunity. Three classes of synthetic CpG-ODNs, class A, B and C, activate cells...

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Autori principali: Martinson, Jeffrey A, Tenorio, Allan R, Montoya, Carlos J, Al-Harthi, Lena, Gichinga, Carolyne N, Krieg, Arthur M, Baum, Linda L, Landay, Alan L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265902/
https://ncbi.nlm.nih.gov/pubmed/17343615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02530.x
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