Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers

BACKGROUND: Chronic hepatitis C virus (HCV) infection results from weak or absent T cell responses. Pegylated-interferon-alpha (IFN-α) and ribavirin, the standard of care for chronic HCV, have numerous immune effects but are not potent T cell activators. A potent immune activator such as TLR9 agonis...

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Библиографические подробности
Главные авторы: Cooper, Curtis L, Ahluwalia, Navneet K, Efler, Susan M, Vollmer, Jörg, Krieg, Arthur M, Davis, Heather L
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430961/
https://ncbi.nlm.nih.gov/pubmed/18541039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-6-3
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