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Interleukin-4 inhibits cyclo-oxygenase-2 expression and prostaglandin E(2) production by human mature dendritic cells

Interleukin-4 (IL-4) is considered the key cytokine for inducing T helper type 2 (Th2) cell differentiation, while interferon-γ and IL-12 are pivotal cytokines for Th1 immune responses. Paradoxically, IL-4 has also been demonstrated to enhance IL-12 production by dendritic cells, suggesting an IL-4-...

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Detalhes bibliográficos
Main Authors: Teloni, Raffaela, Giannoni, Federico, Rossi, Paolo, Nisini, Roberto, Gagliardi, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265872/
https://ncbi.nlm.nih.gov/pubmed/17059508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02482.x
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