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Reduction of urinary 8-epi-prostaglandin F(2α) during cyclo-oxygenase inhibition in rats but not in man
1. 8-epi-prostaglandin (PG) F(2α), a major F(2) isoprostane, is produced in vivo by free radical-dependent peroxidation of lipid-esterified arachidonic acid. Both cyclo-oxygenase isoforms (COX-1 and COX-2) may also form free 8-epi-PGF(2α) as a minor product. It has been recently seen in human volunt...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564876/ https://ncbi.nlm.nih.gov/pubmed/9283716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701321 |
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