Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2.

Prostaglandin (PG) E(1) has been shown to possess anti-inflammatory properties and to modulate vascular reactivity. These activities are sometimes distinct from those of PGE(2), suggesting that endogenously produced PGE(1) may have some beneficial therapeutic effects compared with PGE(2). Increasing...

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Bibliografiske detaljer
Main Authors: Levin, Galit, Duffin, Kevin L, Obukowicz, Mark G, Hummert, Susan L, Fujiwara, Hideji, Needleman, Philip, Raz, Amiram
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222686/
https://ncbi.nlm.nih.gov/pubmed/11939906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011798
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