Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2.

Prostaglandin (PG) E(1) has been shown to possess anti-inflammatory properties and to modulate vascular reactivity. These activities are sometimes distinct from those of PGE(2), suggesting that endogenously produced PGE(1) may have some beneficial therapeutic effects compared with PGE(2). Increasing...

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Main Authors: Levin, Galit, Duffin, Kevin L, Obukowicz, Mark G, Hummert, Susan L, Fujiwara, Hideji, Needleman, Philip, Raz, Amiram
Formato: Artigo
Idioma:Inglês
Publicado: 2002
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222686/
https://ncbi.nlm.nih.gov/pubmed/11939906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011798
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