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Nuclear polyglutamine-containing protein aggregates as active proteolytic centers

Protein aggregates and nuclear inclusions (NIs) containing components of the ubiquitin–proteasome system (UPS), expanded polyglutamine (polyQ) proteins, and transcriptional coactivators characterize cellular responses to stress and are hallmarks of neurodegenerative diseases. The biological function...

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Bibliografische gegevens
Hoofdauteurs: Chen, Min, Singer, Lena, Scharf, Andrea, von Mikecz, Anna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265588/
https://ncbi.nlm.nih.gov/pubmed/18283109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708131
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