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Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein
Nuclear aggregates of polyglutamine (polyQ)-expanded proteins are associated with a number of neurodegenerative diseases including Huntington’s disease (HD) and spinocerebellar ataxias (SCAs). The nuclear deposition of polyQ proteins correlates with rearrangements of nuclear matrix, transcriptional...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544257/ https://ncbi.nlm.nih.gov/pubmed/15964198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2005.05.015 |
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