Important role of matrix metalloproteinase 9 in epileptogenesis

Temporal lobe epilepsy (TLE) is a devastating disease in which aberrant synaptic plasticity plays a major role. We identify matrix metalloproteinase (MMP) 9 as a novel synaptic enzyme and a key pathogenic factor in two animal models of TLE: kainate-evoked epilepsy and pentylenetetrazole (PTZ) kindli...

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Bibliografiset tiedot
Päätekijät: Wilczynski, Grzegorz M., Konopacki, Filip A., Wilczek, Ewa, Lasiecka, Zofia, Gorlewicz, Adam, Michaluk, Piotr, Wawrzyniak, Marcin, Malinowska, Monika, Okulski, Pawel, Kolodziej, Lukasz R., Konopka, Witold, Duniec, Kamila, Mioduszewska, Barbara, Nikolaev, Evgeni, Walczak, Agnieszka, Owczarek, Dorota, Gorecki, Dariusz C., Zuschratter, Werner, Ottersen, Ole Petter, Kaczmarek, Leszek
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2008
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265409/
https://ncbi.nlm.nih.gov/pubmed/18332222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708213
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