Epigenetics of Epileptogenesis-Evoked Upregulation of Matrix Metalloproteinase-9 in Hippocampus

Enhanced levels of Matrix Metalloproteinase-9 (MMP-9) have been implicated in the pathogenesis of epilepsy in humans and rodents. Lack of Mmp-9 impoverishes, whereas excess of Mmp-9 facilitates epileptogenesis. Epigenetic mechanisms driving the epileptogenesis-related upregulation of MMP-9 expressio...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zybura-Broda, Katarzyna, Amborska, Renata, Ambrozek-Latecka, Magdalena, Wilemska, Joanna, Bogusz, Agnieszka, Bucko, Joanna, Konopka, Anna, Grajkowska, Wieslawa, Roszkowski, Marcin, Marchel, Andrzej, Rysz, Andrzej, Koperski, Lukasz, Wilczynski, Grzegorz M., Kaczmarek, Leszek, Rylski, Marcin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978505/
https://ncbi.nlm.nih.gov/pubmed/27505431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159745
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