Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients

BACKGROUND: Combination anti-viral therapies have reduced treatment failure rates by requiring multiple specific mutations to be selected on the same viral genome to impart high-level drug resistance. To determine if the common protease inhibitor resistance mutation L90M is only selected once or rep...

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Hlavní autoři: Kapoor, Amit, Shapiro, Beth, Shafer, Robert W, Shulman, Nancy, Rhee, Soo-Yon, Delwart, Eric L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265302/
https://ncbi.nlm.nih.gov/pubmed/18221530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-7
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