Sequencing-Based Detection of Low-Frequency Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by an RNA/DNA Heteroduplex Generator-Tracking Assay

Drug-resistant viruses may be present as minority variants during early treatment failures or following discontinuation of failed antiretroviral regimens. A limitation of the traditional direct PCR population sequencing method is its inability to detect human immunodeficiency virus type 1 (HIV-1) va...

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Publicado en:	J Virol
Autores principales:	Kapoor, Amit, Jones, Morris, Shafer, R. W., Rhee, Soo-Yon, Kazanjian, Powel, Delwart, Eric L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Vaccines and Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15194787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.13.7112-7123.2004
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