Sequencing-Based Detection of Low-Frequency Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by an RNA/DNA Heteroduplex Generator-Tracking Assay

Drug-resistant viruses may be present as minority variants during early treatment failures or following discontinuation of failed antiretroviral regimens. A limitation of the traditional direct PCR population sequencing method is its inability to detect human immunodeficiency virus type 1 (HIV-1) va...

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Hlavní autoři: Kapoor, Amit, Jones, Morris, Shafer, R. W., Rhee, Soo-Yon, Kazanjian, Powel, Delwart, Eric L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC421662/
https://ncbi.nlm.nih.gov/pubmed/15194787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7112-7123.2004
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