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Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism

Accelerated protein degradation via the ubiquitin–proteasome pathway is the principal cause of skeletal muscle wasting associated with common human disease states and pharmacological treatment with glucocorticoids. Although many protein regulatory factors essential for muscle development and regener...

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Bibliografiske detaljer
Main Authors: Sun, Liping, Trausch-Azar, Julie S., Muglia, Louis J., Schwartz, Alan L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265166/
https://ncbi.nlm.nih.gov/pubmed/18296633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800165105
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