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Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism

Accelerated protein degradation via the ubiquitin–proteasome pathway is the principal cause of skeletal muscle wasting associated with common human disease states and pharmacological treatment with glucocorticoids. Although many protein regulatory factors essential for muscle development and regener...

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Hlavní autoři: Sun, Liping, Trausch-Azar, Julie S., Muglia, Louis J., Schwartz, Alan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265166/
https://ncbi.nlm.nih.gov/pubmed/18296633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800165105
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