Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Although the majority of colorectal cancers exhibit chromosome instability (CIN), only a few genes that might cause this phenotype have been identified and no general mechanism underlying their function has emerged. To systematically identify somatic mutations in potential CIN genes in colorectal ca...

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Autori principali: Barber, Thomas D., McManus, Kirk, Yuen, Karen W. Y., Reis, Marcelo, Parmigiani, Giovanni, Shen, Dong, Barrett, Irene, Nouhi, Yasaman, Spencer, Forrest, Markowitz, Sanford, Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Hieter, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265152/
https://ncbi.nlm.nih.gov/pubmed/18299561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712384105
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