Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Although the majority of colorectal cancers exhibit chromosome instability (CIN), only a few genes that might cause this phenotype have been identified and no general mechanism underlying their function has emerged. To systematically identify somatic mutations in potential CIN genes in colorectal ca...

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Detalhes bibliográficos
Main Authors: Barber, Thomas D., McManus, Kirk, Yuen, Karen W. Y., Reis, Marcelo, Parmigiani, Giovanni, Shen, Dong, Barrett, Irene, Nouhi, Yasaman, Spencer, Forrest, Markowitz, Sanford, Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Hieter, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265152/
https://ncbi.nlm.nih.gov/pubmed/18299561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712384105
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