Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Although the majority of colorectal cancers exhibit chromosome instability (CIN), only a few genes that might cause this phenotype have been identified and no general mechanism underlying their function has emerged. To systematically identify somatic mutations in potential CIN genes in colorectal ca...

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Bibliografische gegevens
Hoofdauteurs: Barber, Thomas D., McManus, Kirk, Yuen, Karen W. Y., Reis, Marcelo, Parmigiani, Giovanni, Shen, Dong, Barrett, Irene, Nouhi, Yasaman, Spencer, Forrest, Markowitz, Sanford, Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Hieter, Philip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265152/
https://ncbi.nlm.nih.gov/pubmed/18299561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712384105
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