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Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species
The host range of retroviruses is influenced by antiviral proteins such as TRIM5, a restriction factor that recognizes and inactivates incoming retroviral capsids. Remarkably, in Owl monkeys (omk), a cyclophilin A (CypA) cDNA has been transposed into the TRIM5 locus, resulting in the expression of a...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265128/ https://ncbi.nlm.nih.gov/pubmed/18287034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709258105 |
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