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Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins

Mammalian cells express several factors that inhibit lentiviral infection and that have been under strong selective pressure. One of these factors, TRIM5, targets the capsid protein of incoming retrovirus particles and inhibits subsequent steps of the replication cycle. By substituting human immunod...

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Hlavní autoři: Kratovac, Zerina, Virgen, Cesar A., Bibollet-Ruche, Frederick, Hahn, Beatrice H., Bieniasz, Paul D., Hatziioannou, Theodora
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447065/
https://ncbi.nlm.nih.gov/pubmed/18417575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00410-08
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