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Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins

Mammalian cells express several factors that inhibit lentiviral infection and that have been under strong selective pressure. One of these factors, TRIM5, targets the capsid protein of incoming retrovirus particles and inhibits subsequent steps of the replication cycle. By substituting human immunod...

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Autores principales: Kratovac, Zerina, Virgen, Cesar A., Bibollet-Ruche, Frederick, Hahn, Beatrice H., Bieniasz, Paul D., Hatziioannou, Theodora
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447065/
https://ncbi.nlm.nih.gov/pubmed/18417575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00410-08
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