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Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system

Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and asthma, and exert their actions through three different combinations of shared receptors. Here we present the crystal structures of the comple...

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書誌詳細
主要な著者: LaPorte, Sherry L., Juo, Z. Sean, Vaclavikova, Jana, Colf, Leremy A., Qi, Xiulan, Heller, Nicola M., Keegan, Achsah D., Garcia, K. Christopher
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265076/
https://ncbi.nlm.nih.gov/pubmed/18243101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.12.030
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