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Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system

Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and asthma, and exert their actions through three different combinations of shared receptors. Here we present the crystal structures of the comple...

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Detalhes bibliográficos
Main Authors: LaPorte, Sherry L., Juo, Z. Sean, Vaclavikova, Jana, Colf, Leremy A., Qi, Xiulan, Heller, Nicola M., Keegan, Achsah D., Garcia, K. Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265076/
https://ncbi.nlm.nih.gov/pubmed/18243101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.12.030
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