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Molecular and structural basis of cytokine receptor pleiotropy in the Interleukin-4/13 system
Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and asthma, and exert their actions through three different combinations of shared receptors. Here we present the crystal structures of the comple...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265076/ https://ncbi.nlm.nih.gov/pubmed/18243101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.12.030 |
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