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Insulin signaling in Caenorhabditis elegans regulates both endocrine-like and cell-autonomous outputs
In C. elegans, insulin signaling affects development, lifespan and stress resistance. Several studies have shown that insulin signaling affects lifespan in an endocrine-like manner from different cells, while the major downstream target of insulin, the FOXO transcription factor encoded by daf-16, ma...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262836/ https://ncbi.nlm.nih.gov/pubmed/17257591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.04.467 |
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