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DAF-2/Insulin-Like Signaling in C. elegans Modifies Effects of Dietary Restriction and Nutrient Stress on Aging, Stress and Growth
BACKGROUND: Dietary restriction (DR) and reduced insulin/IGF-I-like signaling (IIS) are two regimens that promote longevity in a variety of organisms. Genetic analysis in C. elegans nematodes has shown that DR and IIS couple to distinct cellular signaling pathways. However, it is not known whether t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080776/ https://ncbi.nlm.nih.gov/pubmed/18043747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001240 |
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