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Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan

Much excitement has arisen from the observation that decrements in insulin-like signaling can dramatically extend lifespan in the nematode, Caenorhabditis elegans, and fruitfly, Drosophila melanogaster. In addition, there are tantalizing hints that the IGF-I pathway in mice may have similar effects....

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Bibliografiska uppgifter
Huvudupphovsmän: Gami, Minaxi S, Wolkow, Catherine A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413578/
https://ncbi.nlm.nih.gov/pubmed/16441841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00188.x
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