EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level amplifications in 12% of adenocarcinomas of the lung were independently reported recently. Because the EML4-ALK fusion was only shown by a reverse transcription-polymerase...

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Detalhes bibliográficos
Main Authors: Perner, Sven, Wagner, Patrick L, Demichelis, Francesca, Mehra, Rohit, LaFargue, Christopher J, Moss, Benjamin J, Arbogast, Stefanie, Soltermann, Alex, Weder, Walter, Giordano, Thomas J, Beer, David G, Rickman, David S, Chinnaiyan, Arul M, Moch, Holger, Rubin, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259458/
https://ncbi.nlm.nih.gov/pubmed/18320074
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