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EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations
In non-small cell lung cancer, epidermal growth factor receptor gene mutations and anaplastic lymphoma kinase (ALK) gene rearrangements have a major impact upon the level of response to treatment with specific tyrosine kinase inhibitors. This review describes the molecular basis of ALK inhibition, s...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432214/ https://ncbi.nlm.nih.gov/pubmed/22825000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-012-1281-4 |
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