EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations

In non-small cell lung cancer, epidermal growth factor receptor gene mutations and anaplastic lymphoma kinase (ALK) gene rearrangements have a major impact upon the level of response to treatment with specific tyrosine kinase inhibitors. This review describes the molecular basis of ALK inhibition, s...

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Bibliographische Detailangaben
Hauptverfasser: Thunnissen, Erik, Bubendorf, Lukas, Dietel, Manfred, Elmberger, Göran, Kerr, Keith, Lopez-Rios, Fernando, Moch, Holger, Olszewski, Wlodzimierz, Pauwels, Patrick, Penault-Llorca, Frédérique, Rossi, Giulio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2012
Schlagworte:
Review and Perspectives
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432214/
https://ncbi.nlm.nih.gov/pubmed/22825000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-012-1281-4
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