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Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain
BACKGROUND AND PURPOSE: The analgesics, paracetamol and dipyrone are weak inhibitors of the cyclooxygenase isoforms 1 or 2 (COX-1, COX-2) but more potent on COX-3. Both are also weak anti-inflammatory agents, relative to their analgesic and antipyretic activities. In a model of inflammatory pain med...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2259218/ https://ncbi.nlm.nih.gov/pubmed/18157167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707630 |
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