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Inhibition of Hepadnavirus Reverse Transcriptase-ɛ RNA Interaction by Porphyrin Compounds

The hepatitis B virus (HBV) reverse transcriptase (RT) plays a multitude of fundamental roles in the viral life cycle and is the key target in the development of anti-HBV chemotherapy. We report here that the endogenous small molecule iron protoporphyrin IX (hemin) and several related porphyrin comp...

詳細記述

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書誌詳細
主要な著者: Lin, Li, Hu, Jianming
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258913/
https://ncbi.nlm.nih.gov/pubmed/18094191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02147-07
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