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Inhibition of Hepadnavirus Reverse Transcriptase-ɛ RNA Interaction by Porphyrin Compounds
The hepatitis B virus (HBV) reverse transcriptase (RT) plays a multitude of fundamental roles in the viral life cycle and is the key target in the development of anti-HBV chemotherapy. We report here that the endogenous small molecule iron protoporphyrin IX (hemin) and several related porphyrin comp...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258913/ https://ncbi.nlm.nih.gov/pubmed/18094191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02147-07 |
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