Functional and Structural Dynamics of Hepadnavirus Reverse Transcriptase during Protein-Primed Initiation of Reverse Transcription: Effects of Metal Ions

Reverse transcription in hepadnaviruses is primed by the viral reverse transcriptase (RT) (protein priming) and requires the interaction between the RT and a specific viral RNA template termed ɛ. Protein priming is resistant to a number of RT inhibitors that can block subsequent viral DNA elongation...

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Hlavní autoři: Lin, Li, Wan, Fen, Hu, Jianming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395161/
https://ncbi.nlm.nih.gov/pubmed/18400846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02760-07
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