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Functional and Structural Dynamics of Hepadnavirus Reverse Transcriptase during Protein-Primed Initiation of Reverse Transcription: Effects of Metal Ions
Reverse transcription in hepadnaviruses is primed by the viral reverse transcriptase (RT) (protein priming) and requires the interaction between the RT and a specific viral RNA template termed ɛ. Protein priming is resistant to a number of RT inhibitors that can block subsequent viral DNA elongation...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395161/ https://ncbi.nlm.nih.gov/pubmed/18400846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02760-07 |
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