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Wingless Signaling Induces Widespread Chromatin Remodeling of Target Loci

How signaling cascades influence gene regulation at the level of chromatin modification is not well understood. We studied this process using the Wingless/Wnt pathway in Drosophila. When cells sense Wingless ligand, Armadillo (the fly β-catenin) becomes stabilized and translocates to the nucleus, wh...

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Autors principals: Parker, David S., Ni, Yunyun Y., Chang, Jinhee L., Li, Jiong, Cadigan, Ken M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258762/
https://ncbi.nlm.nih.gov/pubmed/18160704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01230-07
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