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Activation of Wingless targets requires bipartite recognition of DNA by TCF
Specific recognition of DNA by transcription factors is essential for precise gene regulation. In Wingless (Wg) signaling in Drosophila, target gene regulation is controlled by TCF, which binds to specific DNA sequences through a HMG domain [1]. However, there is considerable degeneracy in what cons...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105462/ https://ncbi.nlm.nih.gov/pubmed/19062282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.10.047 |
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