Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System

The Wnt/β-catenin signaling pathway plays many important roles in animal development, tissue homeostasis and human disease. Transcription factors of the TCF family mediate many Wnt transcriptional responses, promoting signal-dependent activation or repression of target gene expression. The mechanism...

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Bibliographic Details
Main Authors: Zhang, Chen U., Blauwkamp, Timothy A., Burby, Peter E., Cadigan, Ken M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140642/
https://ncbi.nlm.nih.gov/pubmed/25144371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004509
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