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C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila

Regulation of Wnt transcriptional targets is thought to occur by a transcriptional switch. In the absence of Wnt signaling, sequence-specific DNA-binding proteins of the TCF family repress Wnt target genes. Upon Wnt stimulation, stabilized β-catenin binds to TCFs, converting them into transcriptiona...

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Autori principali: Fang, Ming, Li, Jiong, Blauwkamp, Timothy, Bhambhani, Chandan, Campbell, Nathan, Cadigan, Ken M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500853/
https://ncbi.nlm.nih.gov/pubmed/16710294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601153
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