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Activation of Wingless targets requires bipartite recognition of DNA by TCF

Specific recognition of DNA by transcription factors is essential for precise gene regulation. In Wingless (Wg) signaling in Drosophila, target gene regulation is controlled by TCF, which binds to specific DNA sequences through a HMG domain [1]. However, there is considerable degeneracy in what cons...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Chang, Mikyung V., Chang, Jinhee L., Gangopadhyay, Anu, Shearer, Andrew, Cadigan, Ken M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105462/
https://ncbi.nlm.nih.gov/pubmed/19062282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.10.047
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